Title: Post-Marketing Surveillance of the Safety Profile of Infliximab in 5,000 Japanese Patients with Rheumatoid Arthritis
نویسندگان
چکیده
*: Member of the Committee on Post-Marketing Surveillance of Japan College of Rheumatology 1) Tsutomu Takeuchi MD; Division of Rheumatology and Clinical Immunology, Saitama Medical Center, Saitama Medical University, Saitama, Japan. 2) Yoshihiko Tatsuki; Pharmaceuticals Sales & Marketing Headquarters, Yoshihide Nogami; Compliance & Assurance Headquarters, Tanabe Seiyaku Co., LTD, Osaka, Japan. 3) Naoki Ishiguro MD; Department of Orthopaedic Surgery, Nagoya University School of Medicine, Aichi, Japan. 4) Yoshiya Tanaka MD; The First Department of Internal Medicine, University of Occupational & Environmental Health, School of Medicine, Fukuoka, Japan. 5) Hisashi Yamanaka MD; Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan 6) Masayoshi Harigai MD; Department of Pharmacovigilance and Department of Medicine and Rheumatology, Tokyo Medical and Dental University, Tokyo, Japan. 7) Junnosuke Ryu MD; Department of Orthopaedic Surgery, Nihon University School of Medicine, Tokyo, Japan. 8) Kazuhiko Inoue MD; Department of Orthopaedic Surgery, Tokyo Women's Medical University, Medical Center East, Tokyo, Japan. 9) Hirobumi Kondo MD; Kitasato Institute Medical Center Hospital, Saitama, Japan. 10) Shigeko Inokuma MD; Department of Allergy and Immunological Diseases, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan. 11) Naoyuki Kamatani MD; Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan. 12) Takahiro Ochi MD; National Hospital Organization Sagamihara National Hospital, Kanagawa, Japan. 13) Takao Koike MD; Department of Medicine II, Hokkaido University Graduate School of Medicine, Hokkaido, Japan
منابع مشابه
Postmarketing surveillance of the safety profile of infliximab in 5000 Japanese patients with rheumatoid arthritis.
OBJECTIVES A large-scale postmarketing surveillance (PMS) study was carried out to determine the safety profile of infliximab in Japanese patients with rheumatoid arthritis (RA). METHODS The PMS study was performed for all patients with RA who were treated with infliximab. They were consecutively registered in the PMS study at the initiation of infliximab treatment and were prospectively moni...
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The anti-TNF-alpha chimeric monoclonal antibody infliximab is the first biologic to be approved for rheumatoid arthritis (RA) in Japan, and post-marketing surveillance of all of the Japanese cases treated with infliximab has been conducted to explore the safety of infliximab therapy. In addition, a retrospective clinical study on the notable efficacy and related factors of infliximab therapy in...
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